Abstract

Research on treatments and cures for Lumpy Skin Disease (LSD) has significantly grown in India, where the condition is growing increasingly. The main focus of drug repurposing research is on conventional treatments. The disease is characterised by the skin’s eruption of nodules covering the entire body of the affected animal. The lesions are seen in the upper respiratory tract and mouth. Anorexia, pneumonia, pyrexia and dysgalactia are among the systemic effects. The disease causes loss to the farmer due to declined milk production, abortions, infertility, permanent damage to the hides, and occasional death. However, most of the antiviral drugs are synthetic small molecules, and antiviral plant-derived medicines are yet to be discovered for LSD. The treatment of LSD with ethnoveterinary medicinal formulations has been suggested by the National Dairy Development Board (NDDB). It included plants with various bioactive compounds having antioxidative, anti-inflammatory, immunomodulatory, analgesic, and antiviral properties. These ethnoveterinary medicinal formulations are proven superior when used singly or in combination with existing drugs to enhance the effectiveness of antivirals and increase their bioavailability. The use of medicinal plants and their phytochemicals would relieve the suffering in animals. It can also be the right path for the creation of new affordable drugs through scientific studies.

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