Review Article

Rumen bypass protein: An effective technology for enhancing performance of ruminants

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  • Pages: 43 - 52
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*Corresponding Author Email:  avijitcirb@gmail.com

Received -  20.09.2024, Accepted -  22.11.2024, Published -  01.12.2024

Citation:  Thakur S, Dey A and Kumar S, 2024. Rumen bypass protein: An effective technology for enhancing performance of ruminants. Indian J Anim Health, 63(2-Spl): 43-52, doi: https://doi.org/10.36062/ijah.2024.spl.01124

Protection of feed protein from rumen degradation is important in productive ruminants which need diet with high concentrations of crude protein. The protein supplied through rumen microbial fermentation may fall short of the nutrient demands placed on the animals during the early growth period, lactation, or stress conditions. Protected protein bypasses the rumen and provides additional essential amino acids for absorption in the small intestine. Therefore, inefficient use of the feed nitrogen may be avoided using rumen protein protection technology. Although naturally protected protein sources such as cottonseed cake, maize gluten meal, coconut cake, etc. can be used, protection of feed protein can be achieved through various techniques such as tannin supplementation, formaldehyde treatment, heat treatment alone or in combination with organic acids, or directly protecting amino acids from rumen degradation through various physical and chemical methods such as encapsulation, use of alcohols, tannins, bentonite, aldehydes etc. Supplementation of rumen protected or bypass protein in ruminants increases nutrient utilization, nitrogen retention, and overall amino acid availability without negatively affecting rumen fermentation. Calves supplemented with rumen protected protein demonstrated better growth parameters such as improved average daily gain and feed utilization efficiency. In productive animals, supplementation of bypass protein demonstrated higher milk yields and better overall reproductive performance in terms of early postpartum oestrus, reduced prepubertal period, and improved pregnancy maintenance. Therefore, large-scale application of rumen protected protein technology is an important strategy to achieve quality livestock production and to improve nutrient utilization with minimal wastage of limited feed resources.


Reference

Aasiwal DP, Meena BS, Mahesh MS, Sharma K and Lalremuta C, 2015. Effect of feeding formaldehyde treated rapeseed and cottonseed cakes on milk yield and composition at various stages of lactation and parity in Jersey cows. J Anim Res, 5(1): 15-20

Ani SD and Ajith MK, 2021. Increasing Production of Dairy Animals Through Natural Bypass Nutrients and Organic Minerals. In: Reviews of Veterinary Research-What Next? (Gigin T; Niyas E, Siva Kumar A, Eds), Lulu Publication, Raleigh, USA, ISBN: 978-1-300-21732-9, pp 304- 313

Arisya W, Ridwan R, Ridla M and Jayanegara A, 2019. Tannin treatment for protecting feed protein degradation in the rumen in vitro. J Phys, 1360(1): 012022, doi: 10.1088/1742-6596/1360/1/012022

Arroyo JM, González J, Muñoz J, Alvir MR, Rodríguez CA et al., 2011. In vitro efficiency of combined acid-heat treatments for protecting sunflower meal proteins against ruminal degradation. Animal, 5(8): 1188-1194, doi: 10.1017/S1751731111000279

Arroyo JM, González J, Ouarti M, Silván JM, Ruiz Del Castillo ML et al., 2013. Malic acid or orthophosphoric acid-heat treatments for protecting sunflower (Helianthus annuus) meal proteins against ruminal degradation and increasing intestinal amino acid supply. Animal, 7(2): 223-231, doi: 10.1017/S1751731112001292

Atole AFF and Bestil LC, 2014. Extrapolating bypass protein potential of treated soybean meal by in situ degradation in rumen-fistulated Brahman cattle. Ann Trop Res, 36(1): 50-62

Avila AS, Zambom MA, Faccenda A, Fischer ML, Anschau FA et al., 2020. Effects of black Wattle (Acacia mearnsii) condensed tannins on intake, protozoa population, ruminal fermentation, and nutrient digestibility in Jersey steers. Animals, 10(6): 1011, doi: 10.3390/ani10061011

Bach A, Calsamiglia S and Stern MD, 2005. Nitrogen metabolism in the rumen. J Dairy Sci, 88, E9-E21, doi: 10.3168/jds.S0022-0302(05)73133-7

Bharadwaj A, Sengupta BP and Sethi RK, 2000. Effect of feeding rumen protected and unprotected protein on nutrients intake and reproductive performance of lactating buffaloes. Indian J Anim Sci, 70(4): 428-430

Borucki Castro SI, Phillip LE, Lapierre H, Jardon PW and Berthiaume R, 2007. Ruminal degradability and intestinal digestibility of protein and amino acids in treated soybean meal products. J Dairy Sci, 90(2): 810-822, doi: 10.3168/jds.S0022-0302(07)71565-5

Chandrasekharaiah M, Sampath KT and Praveen US, 2008. Effect of feeding bypass protein on milk production performance crossbred cow. Indian J Anim Sci, 78(5): 527-530

Chandrasekharaiah M, Soren NM and Rao SBN, 2022. Ruminal degradability of bypass fat and protein of certain commonly used feedstuffs in dairy rations. Indian J Anim Sci, 92(4): 471-476, doi: 10.56093/ijans.v92i4.124171

 Chanu YM, Paul SS, Dey A and Andonissamy J, 2024. Deciphering Hyper ammonia -producing bacteria (HAB) in the rumen of water buffaloes (Bubalus bubalis) and their inhibition through plant extracts and essential oils. Microorganisms, 12(10): 2040, doi: 10.3390/microorganisms12102040

Chase LE, Higgs RJ and Van Amburgh ME, 2012. Feeding Low Crude Protein Rations to Dairy Cows-What Have We Learned. In: Proceedings of the 23rd Ruminant Nutrition Symposium. University of Florida, Gainsville, FL, pp 32-42

Chatterjee A and Walli TK, 2000. Effect of formaldehyde treatment at different levels on ruminal and post ruminal digestibility of groundnut cake protein. Indian J Anim Prod Manag, 16(3): 91-95

Chatterjee A and Walli TK, 2003. Effect of formaldehyde treatment on effective protein degradability and in vitro post-ruminal digestibility of mustard cake. Indian J Anim Nutr, 20(2): 143-148

Chen D, Yan J, Shen W, Song Y, Lan X et al., 2020. Effect of inclusion of HMBi in the ration of goats on feed intake, nutrient digestibility, rumen bacteria community and blood serum parameters. J Anim Physiol Anim Nutr, 104(4): 987-997, doi: 10.1111/jpn.13270

Choudhary RK, Roy A, Singh NK, Kumar S and Singh RK, 2020. Effect of bypass protein on milk production and economic of lactating crossbred cows: effect of bypass protein on crossbred cow’s milk production. J AgriSearch, 7(1): 40-43, doi: 10.21921/jas.v7i01.17633

Dey A, Dutta N, Sharma K and Pattanaik AK, 2006. Evaluation of condensed tannins in tropical tree leaves and its impact on in vitro nitrogen degradability of groundnut cake. Anim Nutr Feed Technol, 6(2): 215-222

Dey A, Dutta N, Sharma K and Pattanaik AK, 2008. Effect of dietary inclusion of Ficus infectoria leaves as a protectant of proteins on the performance of lambs. Small Rum Res, 75: 105-114, doi: 10.1016/j.smallrumres.2007.06.013

Dey A, Dutta N, Sharma K and Pattanaik AK, 2009a. Response of dairy cows to dietary supplementation of condensed tannins through Ficus infectoria leaves. Indian J Anim Sci, 79(1): 58-66

Dey A, Dutta N, Sharma K and Pattanaik AK, 2009b. Effect of Ficus infectoria leaves tannins on in vitro rumen fermentation. Indian Vet J, 86(11): 1156-1158

Dhiman TR, Korevaar AC and Satter LD, 1997. Particle size of roasted soybeans and the effect on milk production of dairy cows. J Dairy Sci, 80(8): 1722-1727, doi: 10.3168/jds.S0022-0302(97)76104-6

Díaz-Royón F, Arroyo JM, Sánchez-Yélamo MD and González J, 2016. Sunflower meal and spring pea ruminal degradation protection using malic acid or orthophosphoric acid-heat treatments. Anim Prod Sci, 56(12): 2029-2038, doi: 10.1071/AN14669

Eissa HA, Idreese A, Hamid G and Yousif F, 2014. Heat treated ground nut cakes as a bypass protein source. J Agric Vet Sci, 6(2): 125-132

El-Shabrawy HM, El-Deeb MM, Etman KE and Mehrez AZ, 2010. Effect of protected protein on growth performance of crossbred friesian calves fed corn silage-based diets. J Anim Poult Prod, 1(10): 441-454, doi: 10.21608/jappmu.2010.86256

Gao W, Chen A, Zhang B, Kong P, Liu C et al., 2015. Rumen degradability and post-ruminal digestion of dry matter, nitrogen and minoacids of three protein supplements. Asian-Australasian J Anim Sci, 28(4): 485-493, doi: 10.5713/ajas.14.0572

Garnsworthy PC, Saunders N, Goodman JR and Marsden M, 2021. Evaluation of rumen protected rapeseed expeller (NovaPro) as an alternative to soya bean meal in dairy cow diets. Anim Feed Sci Technol, 273: 114816

Gonzalez J, Arroyo JM and Ouarti M, 2009. Efficacy of the Combined Use of Acids and Heat to Protect Protein from Sunflower Meal Against Rumen Degradation: 2. Feed Amino Acid Supply. In: Ruminant Physiology, pp 188-189 ‘Proceedings of the XI International Symposium on Ruminant Physiology’, At: Clermont-Ferrand, France. Wageningen Academic Publishers, The Netherlands

Gonzalez J, Rodr?guez CA, Andrés SG and Alvir MR, 1998. Rumen degradability and microbial contamination of fish meal and meat meal measured by the in situ technique. Anim Feed Sci Technol, 73(1-2): 71-84, doi: 10.1016/S0377-8401(98)00132-1 

Harlow BE, Bryant RW, Cohen SD, O'Connell SP and Flythe MD, 2016. Degradation of spent craft brewer's yeast by caprine rumen hyper ammonia?producing bacteria. Lett Appl Microbiol, 63(4): 307-312, doi: 10.1111/lam.12623

Henke A, Westreicher-Kristen E, Molkentin J, Dickhoefer U, Knappstein K et al., 2017. Effect of dietary quebracho tannin extract on milk fatty acid composition in cows. J Dairy Sci, 100(8): 6229-6238, doi: 10.3168/jds.2016-12149

Huhtanen P and Hristov AN, 2009. A meta-analysis of the effects of dietary protein concentration and degradability on milk protein yield and milk N efficiency in dairy cows. J Dairy Sci, 92(7): 3222-3232, doi: 10.3168/jds.2008-1352

Idowu M, Taiwo G, Sidney T, Treon E, Leal Y et al., 2024. Effects of rumen-bypass protein supplement on growth performance, hepatic mitochondrial protein complexes, and hepatic immune gene expression of beef steers with divergent residual feed intake. Plos One, 19(7): e0293718, doi: 10.1371/journal.pone.0293718

Jadhav MD, Choubey M, Patel VR, Vahora SG, Sorathiya KK et al., 2018. Effect of graded level of bypass protein on metabolites of rumen fermentation in Surti buffalo heifers. Indian Vet J, 95(02): 29-31

Jadhav MD, Choubey M, Sorathiya KK, Patel VR and Vahora SG, 2018. Effect of bypass protein on reproductive performance of Surti buffalo heifers. Int J Chem Stud, 6(4): 2423-2424

Jones RA, Mustafa AF, Christensen DA and McKinnon JJ, 2001. Effects of untreated and heat-treated canola presscake on milk yield and composition of dairy cows. Animal Feed Sci Technol, 89(1-2): 97-111, doi: 10.1016/S0377-8401(00)00219-4

Kazemi-Bonchenari M, Dehghan-Banadaky M, Fattahnia F, Saleh-Bahmanpour A, Jahani-Moghadam M et al., 2020. Effects of linseed oil and rumen undegradable protein:rumen degradable protein ratio on performance of Holstein dairy calves. Br J Nutr, 123(11): 1247-1257, doi: 10.1017/S0007114520000586

Kumari A, Kar D, Gulati HK, Akbar MA, Sihag S et al., 2017. Influence of feeding different sources of bypass protein on growth performance, hematology and economics in Murrah buffalo heifers. Indian J Anim Res, 51(4): 706-711, doi: 10.18805/ijar.11460

Loregian KE, Pereira DA, Rigon F, Magnani E, Marcondes MI et al., 2023. Effect of tannin inclusion on the enhancement of rumen undegradable protein of different protein sources. Ruminants, 3(4): 413-424, doi: 10.3390/ruminants3040034 

Mane SH, Mandakmale SD, Nimbalkar CA, Kankhare DH and Lokhande AT, 2017. Economics of feeding protected protein and protected fat on crossbred cattle. Indian J Anim Res, 51(6): 1080-1085, doi: 10.18805/ijar.v0iOF.9121

Maska?ová I, Vajda V and Lacková PT, 2024. Estimation of ruminal digestibility of nutrient and intestinal digestibility of un-degradable proteins at different feedstuffs. Acta fytotechn zootechn, 27(1): 8-17, doi: 10.15414/afz.2024.27.01.8-17

Mazinani M, Ali Naserian A, Rude B, Valizadeh R and Tahmasbi A, 2019. Production of rumen-protected essential amino acids with chemical technique. Biosci Biotechnol Res Asia, 16(04): 789-795, doi: 10.13005/bbra/2795

Mazinani M, Memili E and Rude BJ, 2022. Harnessing the value of rumen protected amino acids to enhance animal performance - A review. Ann Anim Sci, 22(1): 43-62, doi: 10.2478/aoas-2021-0018

Mazinani M, Naserian AA, Rude BJ, Tahmasbi AM and Valizadeh R, 2020. Effects of feeding rumen–protected amino acids on the performance of feedlot calves. J Adv Vet Anim Res, 7(2): 229, doi: 10.5455/javar.2020.g414

McIntosh FM, Williams P, Losa R, Wallace RJ, Beever DA et al., 2003. Effects of essential oils on ruminal microorganisms and their protein metabolism. Appl Environ Microbiol, 69(8): 5011-5014, doi: 10.1128/AEM.69.8.5011-5014.2003

Micek P, S?ota K and Górka P, 2020. Effect of heat treatment and heat treatment in combination with lignosulfonate on in situ rumen degradability of canola cake crude protein, lysine, and methionine. Can J Anim Sci, 100(1): 165-174, doi: 10.1139/cjas-2018-0216

NDDB, 2006. Bypass Protein Supplement: An Economical Way to Increasing Dairy Milk Production. Anand Press, India [Cited 2024 Nov 18]. Available from:  https://www.nddb.coop/sites/default/files/pdfs/Bypass_Protein%5B1%5D.pdf

Orlandi T, Kozloski GV, Alves TP, Mesquita FR and Ávila SC, 2015. Digestibility, ruminal fermentation and duodenal flux of amino acids in steers fed grass forage plus concentrate containing increasing levels of Acacia mearnsii tannin extract. Anim Feed Sci Technol, 210: 37-45, doi: 10.1016/j.anifeedsci.2015.09.012

Osti NP, Mandal P, Bhola S and Shrestha S, 2013. Milk yield response of bypass protein feeding (soybean meals) in dairy animals. Buff Bul, 32(2): 834-839

Ouarti M, González J, Fernandes LFJ, Alvir MR and Rodríguez CA, 2006. Malic acid combined with heat treatment to protect protein from soybean meal against rumen degradation. Anim Res, 55(3): 165-175, doi:  10.1051/animres:2006014

Parmar AB, Patel DC, Sarvaiya NP, Parmar AP, Dhami AJ et al., 2023. The formaldehyde treated guar meal and prill fat, agro industrial by-products as dietary rumen protected protein and energy source: improves growth performance, feed conversion, nutrient utilization, microbial protein synthesis, blood metabolites and economic efficiency in growing dairy buffalo (Bubalus bubalis) calves. Trop Anim Health Prod, 55(1): 17, doi: 10.1007/s11250-022-03434-x

Patel VR, Gupta RS and Jani VR, 2012a. Effect of feeding bypass protein on growth, body measurements and nutrient utilization in growing buffalo heifers: A field trial. Indian J Anim Nutr, 29(2): 152-156

Patel VR, Gupta RS, Parnerkar S, Jani VR and Garg DD, 2012b. Performance of buffalo heifers fed on bypass protein: An on-farm appraisal. Anim Nutr Feed Technol, 12(3): 395-402, doi: 10.13140/RG.2.2.12484.24966

Paul SS, Chanu YM and Dey A, 2016. Options for improving nitrogen utilization efficiency in ruminants. Indian J Anim Nutri, 33(1): 1-10

Paya H, Taghizadeh A, Janmohammadi H, Moghaddam GA, Khani AH et al., 2014. Effects of microwave irradiation on in vitro ruminal fermentation and ruminal and post-ruminal disappearance of safflower seed. J Biodivers Environ Sci, 5(2): 349-356

Pitta DW, Indugu N, Vecchiarelli B, Hennessy M, Baldin M et al., 2020. Effect of 2-hydroxy-4-(methylthio) butanoate (HMTBa) supplementation on rumen bacterial populations in dairy cows when exposed to diets with risk for milk fat depression. J Dairy Sci, 103(3): 2718-2730, doi: 10.3168/jds.2019-17389

Prasetiyono BW, Subrata A and Tampoebolon BI, 2018. In Vitro Ruminal Degradability of Soybean Meal Protein Protected with Natural Tannin. IOP Conference Series: Earth Environmental Science, 119: 012016, doi: 10.1088/1755-1315/119/1/012016

Preston TR, Do HQ, Khoa TD, Hao TP and Leng RA, 2013. Protein solubility of fish meal and groundnut meal and methane production in an in vitro incubation. Livest Res Rural Dev, 25(1)

Putri EM, Zain M, Warly L and Hermon H, 2021. Effects of rumen-degradable-to-undegradable protein ratio in ruminant diet on in vitro digestibility, rumen fermentation, and microbial protein synthesis. Vet World, 14(3): 640-648, doi: 10.14202/vetworld.2021.640-648

Putri EM, Zain M, Warly L, Hermon H, 2019. In vitro evaluation of ruminant feed from West Sumatera based on chemical composition and content of rumen degradable and rumen undegradable proteins. Vet World, 12(9): 1478-1483, doi: 10.14202/vetworld.2019.1478-1483

Ramachandra KS and Sampath KT, 1995. Effect of formaldehyde treatment of groundnut cake protein on its in-situ degradability and in-vivo digestibility. Indian J Dairy Sci, 48(12): 664-667

Ratika KH, 2018. Performance of transition buffaloes FED diet supplemented with rumen protected methionine, lysine and choline. PhD Thesis submitted to ICAR- National Dairy Research Institute (Deemed University), Karnal, Haryana, India

Reynal SM and Broderick GA, 2003. Effects of feeding dairy cows protein supplements of varying ruminal degradability. J Dairy Sci, 86(3): 835-843, doi: 10.3168/jds.S0022-0302(03)73666-2

Rosmalia A, Permana IG, Despal D and Zahera R, 2021. Estimation rumen degradable protein of local feeds in dairy cattle using in sacco method. IOP Conf Ser: Earth Environ Sci, 883(1): 012010, doi: 10.1088/1755-1315/883/1/012010  

Schwab CG and Broderick GA, 2017. A 100-Year review: Protein and amino acid nutrition in dairy cows. J Dairy Sci, 100(12): 10094-10112, doi: 10.3168/jds.2017-13320

Shelke SK, Thakur SS and Amrutkar SA, 2012. Effect of feeding protected fat and proteins on milk production, composition and nutrient utilization in Murrah buffaloes (Bubalus bubalis). Anim Feed Sci Technol, 171(2-4): 98-107, doi: 10.1016/j.anifeedsci.2011.10.003

Sherasia PL, MR Garg and BM Bhanderi, 2010. Study on the effect of incorporating rumen protected de-oiled rice bran on milk production in the ration of crossbred cows. Indian J Dairy Sci, 63: 205-208

Sorathiya KK, Choubey M, Patel VR, Vahora SG, Garg DD et al., 2015. Effect of feeding formaldehyde treated protein on nutrient utilization and economics in Surti buffalo heifers. Indian J Anim Sci, 85(12): 65-70

Spore TJ, Carlson ZE, Erickson Erickson GE, Klopfenstein TJ and Watson AK, 2019. Effects of Supplemental Soypass in Forage-Based Diets Containing Distillers Grains on Performance of Growing Steers, Nebraska Beef Cattle Reports, University of Nebraska, Lincoln, USA

Sultan JI, Javaid A, Nadeem M, Akhtar MZ and Mustafa MI, 2009. Effect of varying ruminally degradable to ruminally undegradable protein ratio on nutrient intake, digestibility and N metabolism in Nili Ravi buffalo calves (Bubalus bubalis). Livest Sci, 122(2-3): 130-133, doi: 10.1016/j.livsci.2008.08.004g

Teixeira PD, Tekippe JA, Rodrigues LM, Ladeira MM, Pukrop JR et al., 2019. Effect of ruminally protected arginine and lysine supplementation on serum amino acids, performance, and carcass traits of feedlot steers. J Anim Sci, 97(8): 3511-22, doi: 10.1093/jas/skz191

Thakur S, Dey A, Berwal RS and Sihag S, 2023. Malic acid-heat treatment of oil cakes enhances rumen undegradable protein for effective protein utilization in buffaloes (Bubalus bubalis). Indian J Anim Health, 62(Spl-2): 212-221, doi: 10.36062/ijah.2023.spl.02023

Thapa P, Pandey T, Acharya R, Dhital B and Paklihawa R, 2019. Effect of by-pass protein supplements on milk production of dairy cattle. J Agric Nat Resour, 2(1): 171-179, doi: 10.3126/janr.v2i1.26062

Tiwari MR, Jha PK, Pant SR, Acharya MP, Thapa P et al., 2018. Effect of bypass protein supplement on milk production in Jersey cow: bypass protein supplementation in dairy cow. Bangladesh J Anim Sci, 47(2): 98-104

Toledo MZ, Baez GM, Garcia-Guerra A, Lobos NE, Guenther JN et al., 2017. Effect of feeding rumen-protected methionine on productive and reproductive performance of dairy cows. PloS One, 12: e0189117, doi: 10.1371/journal.pone.0189117

Uddin MJ, Khandaker ZH, Khan MJ and Khan MMH, 2015. Dynamics of microbial protein synthesis in the rumen- A review. Ann Vet Anim Sci, 2(5): 116-131

Van Rensburg W, 2024. Manipulation of the rumen environment to increase rumen undegradable protein fraction of feedstuffs. Doctoral dissertation, Stellenbosch University, Stellenbosch, South Africa

Walli TK, 2005. Bypass protein technology and the impact of feeding bypass protein to dairy animals in tropics: A review. Indian J Anim Sci, 75(1): 135-142

Wankhede SM and Kalbande VH, 2001. Effect of feeding bypass protein with urea treated grass on the performance of Red Kandhari calves. Asian-Australasian J Anim Sci, 14(7): 970-973

Wright TC, Moscardini S, Luimes PH, Susmel P and Mcbride BW, 1998. Effects of rumen-undegradable protein and feed intake on nitrogen balance and milk protein production in dairy cows. J Dairy Sci, 81(3): 784-793, doi: 10.3168/jds.S0022-0302(98)75635-8

Yanza YR, Fitri A, Suwignyo B, Hidayatik N, Kumalasari NR et al., 2021. The utilisation of tannin extract as a dietary additive in ruminant nutrition: A meta-analysis. Animals, 11(11): 3317, doi: 10.3390/ani11113317

Zain M, Despal, Tanuwiria UH, Pazla R, Putri EM et al., 2023. Evaluation of legumes, roughages, and concentrates based on chemical composition, rumen degradable and undegradable proteins by in vitro method. Int J Vet Sci, 12(4): 528-538, doi: 10.47278/journal.ijvs/2022.218